Periodontal diseases, including gingivitis and periodontitis, are a global oral health problem.Porphyromonas gingivalis, a key pathogen involved in the onset of periodontitis, is able to colonize the subgingival epithelium and invade the underlying connective tissue due to the contribution of cysteine proteases known as gingipains.In this study, we
The direct medical cost of type 2 diabetes mellitus in South Africa: a cost of illness study
Background: Type 2 diabetes mellitus (T2DM) is known to require continuous clinical care read more and management that consumes significant health-care resources.These costs are not well understood, particularly in low- and middle-income countries.Objective: The aim of this study was to estimate the direct medical costs associated with T2DM in the
A novel yeast-based recombination method to clone and propagate diverse HIV-1 isolates
Replication studies on human immunodeficiency virus 1 (HIV-1) rely on a few laboratory strains that are divergent from dominant HIV-1 subtypes in the epidemic.Several phenotypic differences between diverse HIV-1 ngetikin isolates and subtypes could affect vaccine development and treatment, but this research field lacks robust cloning/virus producti
An integral assessment of landslide dams generated by the occurrence of rainfall-induced landslide and debris flow hazard chain
Landslides caused by here rainfall are one of the most frequent causes of disasters in tropical countries and mountainous terrain and can block rivers generating landslide dams.This paper presents a methodology for the estimation of the obstruction of water streams generated by rainfall-induced shallow landslides.The spatial distribution of the lan
Is Self-Determined Motivation a Useful Agent to Overcome Perceived Exercise Barriers in Patients With Type 2 Diabetes Mellitus?
Background: Devising a program to increase physical activity (PA)/exercise behavior in patients with type 2 diabetes mellitus (T2DM) can meet with limited effectiveness in real-world settings because of the variety of barriers to PA/exercise that individuals need to overcome.An alternative approach is to explore whether targeting motivation as a fa